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Clinical Trials/NCT03689959
NCT03689959
Completed
Not Applicable

Correction of Fixed Knee Flexion Deformity in Children Using Eight-plate Hemiepiphysiodesis

Assiut University1 site in 1 country23 target enrollmentNovember 1, 2018
ConditionsKnee Deformity

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Knee Deformity
Sponsor
Assiut University
Enrollment
23
Locations
1
Primary Endpoint
Degree of flexion deformity
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The study aims to assess the effectiveness of hemiephysiodesis using eight plates in correction of fixed knee flexion deformities in children.

Detailed Description

Flexion contractures of the knee are quite disabling. They produce deleterious effects on knee biomechanics, quadriceps function, energy expenditure during gait and the overall ability to ambulate. These deformities occur secondary to a number of different etiologies including; congenital, traumatic, inflammatory and neuromuscular disorders with cerebral palsy (CP) being on the top of the list. The main aim of correction of sagittal plane deformities of the knee is to restore the range of motion. Surgical options available for correction of knee flexion contractures include soft tissue modification, acute correction by osteotomies, gradual correction by external fixators and growth modulation by hemiephysiodesis.Extensive soft tissue surgery may be needed for correction of knee deformities with potential risk of neurovascular damage and wound complications. Supracondylar extension osteotomies have been widely used, however prolonged immobilization and associated neurovascular insults have always been major concerns. External fixators are cumbersome and may produce muscle tethering and pin tract infections. There are few studies in the literature reporting the use of anterior hemiepiphysiodesis for correction of knee flexion contracture. Our study question can be summarized as follows; Is hemiepiphysiodesis by eight plates effective for correction of fixed knee flexion deformities in children ?

Registry
clinicaltrials.gov
Start Date
November 1, 2018
End Date
March 1, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mohamed Yahya Abdel Azeem Hassanein

Principal Investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • Fixed knee flexion deformity more than 10°
  • Unilateral or bilateral cases
  • 12 months or more predicted growth remaining
  • No response to non-operative treatment (physical therapy, bracing, casting);
  • Recurrent cases

Exclusion Criteria

  • Dynamic deformities due to spasticity
  • Deformities responding to conservative treatment

Outcomes

Primary Outcomes

Degree of flexion deformity

Time Frame: One year

The angle between the anterior borders of thigh and leg measured clinically with a goniometer

Secondary Outcomes

  • Complications(One year)
  • Rate of correction(One year)

Study Sites (1)

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