Collection of Human Tissue Samples From the Neck Region for Characterization of Its Molecular and Biochemical Signatures
Overview
- Phase
- Not Applicable
- Intervention
- Adults presenting for surgery in the neck area
- Conditions
- Obesity
- Sponsor
- AdventHealth Translational Research Institute
- Enrollment
- 34
- Locations
- 1
- Primary Endpoint
- Collection of brown adipose neck tissue
- Status
- Completed
- Last Updated
- 15 days ago
Overview
Brief Summary
The purpose of the study is to gather tissue (from the neck region), specimens (blood and urine) and medical record data from many patients and store them in one place so that scientists have the information they need to conduct research and learn about new ways to predict, identify and treat illness, specifically those related to obesity and diabetes.
Detailed Description
This protocol is designed to actively collect biospecimens (specifically, tissue from the neck region) and clinical data for donation to the TRI-MD, specifically, Dr. Sparks' laboratory. These specimens and data will be available to Dr. Sparks for future research activity in accordance with the Florida Hospital and Translational Research Institute for Metabolism and Diabetes (TRI) policies.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Adults aged 18 and older presenting for surgery in the neck area
- •Able to provide informed consent
Exclusion Criteria
- •Unable to provide informed consent
Arms & Interventions
Adults presenting for surgery in the neck area
Intervention: Adults presenting for surgery in the neck area
Outcomes
Primary Outcomes
Collection of brown adipose neck tissue
Time Frame: Day of scheduled surgery
Any tissue deemed suitable by the surgeon and/or the research team during the neck surgery for the study's research objectives will be removed and collected for donation to this protocol. When there is enough tissue available, half will be snap frozen for extraction of DNA, RNA and protein. The other half will be cryopreserved for the future production of viable cells. When there is not enough tissue, the person collecting the samples will determine the processing. For research purposes, we aim to collect up to 500mg of each tissue.