Evaluation of the efficacy of allogeneic umbilical cord derived hematopoietic and mesenchymal stem cells on developmental functions of spastic cerebral palsy patients between 4-14 years old in comparison with control group , A Clinical trial phase II

Tehran University of Medical Sciences0 个研究点目标入组 108 人开始时间: 待定最近更新: 2019年8月26日

试验速览

暂无简介。

•Spastic cerebral palsy (Diparetic , Quadriparetic)
•Ages between 4 - 14 years
•Gross motor function classification (GMFC) between 2 -5
•No seizure disorder or with controlled seizure
•Evidence of definite acquired abnormal imaging findings compatible with Cerebral Palsy
•Informed consent taken from their parents

•Normal brain MRI
•Progressive neurological diseases ( for example leukodystrophy or neurometabolic disorders)
•Congenital Cortical malformations
•Toxoplasmosis Others Rubella Cytomegalovirus Hepatitis (TORCH) infections
•Other types of cerebral palsy including athetoid , atonic , ataxic , and mixed type
•Acute intercurrent infections such as Hepatitis C Virus ( HCV), Hepatitis B Virus (HBV) ,Human Immunodeficiency Virus (HIV)
•Hemorrhagic diathesis
•Severe anemia ( Hemoglobin less than 8 )
•Ventilator dependent pulmonary diseases
•Renal insufficiency
•Severe liver dysfunction

发起方