Selective Laser Trabeculoplasty After Failed Phacoemulsification With Eximer Laser Trabeculectomy

Not Applicable

Completed

• Conditions: Open Angle Glaucoma; Cataract; Ocular Hypertension
• Interventions: Procedure: Selective Laser Trabeculoplasty

• Registration Number: NCT02434250
• Lead Sponsor: University of Zurich

Brief Summary

The aim of this study is to evaluate the efficacy of selective laser trabeculoplasty after a prior failed phacoemulsification and Eximer Laser Trabeculectomy.

Detailed Description

This study evaluates the efficacy of selective laser trabeculoplasty after a failed combined procedure of phacoemulsification cataract extraction with intraocular lens implantation plus Eximer Laser Trabeculectomy in open angle glaucoma or ocular hypertension. The success of SLT will be determined by the intraocular pressure and number of hypotensive drugs.

Study Timeline

• Study First Submitted: 2015-01-29
• Study First Submitted QC: 2015-04-29
• Study Start: 2015-05
• Study First Posted: 2015-05-05
• Primary Completion: 2016-10
• Study Completion: 2016-11
• Status Verified: 2017-06
• Last Update Submitted: 2017-06-19
• Last Update Posted: 2017-06-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 203

Inclusion Criteria

• diagnosis of open angle glaucoma or ocular hypertension
• and diagnosis of cataract

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Exclusion Criteria

• diagnosis of angle closure glaucoma
• any optic neuropathy other than glaucoma

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
SLT arm	Selective Laser Trabeculoplasty	Patient receiving 'Selective Laser Trabeculoplasty' (SLT) due to failed Phacoemulsification Cataract Extraction with Intraocular Lens Implantation combined with Eximer Laser Trabeculectomy (phaco-ELT) in Open Angle Glaucoma and Ocular Hypertension to control intraocular pressure and/or glaucoma progression.

Primary Outcome Measures

Name	Time	Method
Efficacy intraocular pressure	t0 and t=12 month	Efficacy as measured by decrease in intraocular pressure from baseline
Efficacy medication	t0 and t=12 month	as measured by decrease in number of used hypotensive medications

Secondary Outcome Measures

Name	Time	Method
Efficacy visual acuity	t0 and t=12 month	Efficacy as increase in best corrected visual acuity

Trial Locations

Locations (1)

Department of Ophthalmology; 🇨🇭 Zurich, ZH, Switzerland