Is use of combination of Acitretin capsule and topical triamcinolone gel better than triamcinolone gel alone in treatment of lichen planus of mouth.
- Conditions
- Health Condition 1: K121- Other forms of stomatitis
- Registration Number
- CTRI/2018/11/016448
- Lead Sponsor
- PGIMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
1.Patients with symptomatic oral lichen planus.
2.Age - 18 years or more
1.Any active treatment for oral lichen planus (OLP) in preceding 4 weeks.
2.Presence of any contraindications for acitretin use such as
a.pregnant and lactating women.
b.leucopenia with leucocyte count <4000 â??mm3
c.liver enzymes >2 times the upper limit of reference range
d.Moderate to severe cholesterol and triglycerides elevation
e.Deranged renal function test
3.Females of reproductive age group who have not completed their family or are not willing to use contraception as required.
4.Patients on any other immunosuppressive, immunomodulatory drugs or on drugs that has significant interaction with acitretin.
5.Dental filling with oral lichenoid reaction.
6.Patients who are unable to attend proposed regular follow-up visits.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method