A placebo controlled double blinded randomized controlled trial comparing the combination of oral acitretin and topical steroids with topical steroid monotherapy in symptomatic oral lichen planus

PGIMER0 个研究点目标入组 0 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•1.Any active treatment for oral lichen planus (OLP) in preceding 4 weeks.
•2.Presence of any contraindications for acitretin use such as
•a.pregnant and lactating women.
•b.leucopenia with leucocyte count <4000 â??mm3
•c.liver enzymes >2 times the upper limit of reference range
•d.Moderate to severe cholesterol and triglycerides elevation
•e.Deranged renal function test
•3.Females of reproductive age group who have not completed their family or are not willing to use contraception as required.
•4.Patients on any other immunosuppressive, immunomodulatory drugs or on drugs that has significant interaction with acitretin.
•5.Dental filling with oral lichenoid reaction.
•6.Patients who are unable to attend proposed regular follow-up visits.

发起方