Comparative study of tunneling bloc biopsy versus EUS-fine needle aspiration for GI subepithelial tumor (a prospective comparative study in the same case)
- Conditions
- Gastrointestinal submucosal tumor
- Registration Number
- JPRN-UMIN000006754
- Lead Sponsor
- Kagawa Medical University
- Brief Summary
The study was a non-randomized, prospective comparative study with crossover design in patients with endoluminal gastric subepithelial lesions (SELs). Forty-three patients, including 29 cases with lesions <2 cm were enrolled. A crossover design with two intervention phases (Group A: EUS-guided fine needle aspiration (FNA) followed by STB for 23 SELs, Group B: STB followed by FNA for 20 SELs) was implemented. The primary outcome was the diagnostic yield (DY). Secondary outcomes were technical success rate, procedure time, complication rate, and sample quality. Results: The DY of STB was significantly higher than that of FNA (100% vs. 34.8%) in group A, including 100% in overall STB. The technical success rate of STB was significantly higher than that of FNA (100% vs. 56.5%), whereas the median procedure time of STB was significantly longer than that of FNA (37 minutes vs. 18 minutes). The median specimen area of STB samples was markedly larger than that of FNA samples (5.54 mm2 vs. 0.69 mm2). No complications occurred in either method. Conclusions: STB had significantly superior diagnostic ability and a more adequate sample quality than FNA for endoluminal gastric SELs, indicating the suitability of STB for small SELs.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
extraluminal tumor
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immunohistological diagnostic ratio complication rate
- Secondary Outcome Measures
Name Time Method technical success rate procedure time biopsy frequency