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临床试验/NCT05291065
NCT05291065招募中不适用

Impact of Different Pre-exercise Breakfast Composition on Post-exercise Glycaemic Response, Appetite and Energy Balance

National Taiwan Normal University1 个研究点 分布在 1 个国家目标入组 12 人开始时间: 2022年3月13日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
入组人数
12
试验地点
1
主要终点
Metabolic health

研究概览

简要总结

This project aims to investigate the impact of acute bout of submaximal exercise under different pre-exercise dietary conditions (fasted state versus high carbohydrate breakfast versus high protein breakfast) on postprandial glycaemic, appetite regulation and energy balance.

详细描述

Participants will be asked to arrive to the laboratory between 08:00 and 9:00 am after not eating for between 12-14 hours i.e. in a fasted state (water intake is permitted and encouraged). Participants will then be given one of three test drinks (i.e., breakfast): 1) water only; 2) high carbohydrate drink; or 3) high protein (whey protein) drink. Each of these drinks will also contain 500 mL of water and artificial sweetener. 2 h after breakfast, participants will then exercise on a treadmill for 45 min followed by a 2-h oral glucose tolerance test (OGTT) and 30 min ad libitum lunch intake. Blood samples, blood pressures and questionnaire (e.g., appetite and mood) will be collected in a regular pattern throughout the trials. Cognitive functions will be tested at baseline, pre-exercise and 2 h post-exercise. Energy balance will be assessed using food diary and an accelerometer for the rest of the day after leaving the laboratory until midnight.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Basic Science
盲法
Double (Participant, Investigator)

盲法说明

Participants and Researchers will be blinded to the interventions.

入排标准

年龄范围
30 Years 至 55 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Healthy physical active men (self-reported regular exercise at least 30 min moderate-intensity 3 times per week)
  • Aged between 30 to 55 years
  • Weight stable for more than 3 months (no change in weight +/- 3%)
  • Non-smoker

排除标准

  • Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
  • Taking medications that may influence lipid or carbohydrate metabolism or immune system function
  • Physically inactive

结局指标

主要结局

Metabolic health

时间窗: 150 minutes

Changes in blood glycaemic and insulinaemic responses post-exercise between trials

次要结局

  • Cognition(305 minutes)
  • Visual analogue scale (VSA)(305 minutes)
  • Substrate oxidation(305 minutes)
  • Inflammation(305 minutes)
  • Lipid profile(150 minutes)
  • Blood pressure(305 minutes)
  • Gut hormones(150 minutes)
  • Appetite(30 minutes)
  • Energy balance(480 minutes)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yung-Chih Chen

Principal Investigator

National Taiwan Normal University

研究点 (1)

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