Skip to main content
Clinical Trials/NCT05291065
NCT05291065
Recruiting
Not Applicable

Impact of Different Pre-exercise Breakfast Composition on Post-exercise Glycaemic Response, Appetite and Energy Balance

National Taiwan Normal University1 site in 1 country12 target enrollmentMarch 13, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Metabolic Health
Sponsor
National Taiwan Normal University
Enrollment
12
Locations
1
Primary Endpoint
Metabolic health
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

This project aims to investigate the impact of acute bout of submaximal exercise under different pre-exercise dietary conditions (fasted state versus high carbohydrate breakfast versus high protein breakfast) on postprandial glycaemic, appetite regulation and energy balance.

Detailed Description

Participants will be asked to arrive to the laboratory between 08:00 and 9:00 am after not eating for between 12-14 hours i.e. in a fasted state (water intake is permitted and encouraged). Participants will then be given one of three test drinks (i.e., breakfast): 1) water only; 2) high carbohydrate drink; or 3) high protein (whey protein) drink. Each of these drinks will also contain 500 mL of water and artificial sweetener. 2 h after breakfast, participants will then exercise on a treadmill for 45 min followed by a 2-h oral glucose tolerance test (OGTT) and 30 min ad libitum lunch intake. Blood samples, blood pressures and questionnaire (e.g., appetite and mood) will be collected in a regular pattern throughout the trials. Cognitive functions will be tested at baseline, pre-exercise and 2 h post-exercise. Energy balance will be assessed using food diary and an accelerometer for the rest of the day after leaving the laboratory until midnight.

Registry
clinicaltrials.gov
Start Date
March 13, 2022
End Date
January 1, 2024
Last Updated
3 years ago
Study Type
Interventional
Study Design
Crossover
Sex
Male

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Yung-Chih Chen

Principal Investigator

National Taiwan Normal University

Eligibility Criteria

Inclusion Criteria

  • Healthy physical active men (self-reported regular exercise at least 30 min moderate-intensity 3 times per week)
  • Aged between 30 to 55 years
  • Weight stable for more than 3 months (no change in weight +/- 3%)
  • Non-smoker

Exclusion Criteria

  • Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
  • Taking medications that may influence lipid or carbohydrate metabolism or immune system function
  • Physically inactive

Outcomes

Primary Outcomes

Metabolic health

Time Frame: 150 minutes

Changes in blood glycaemic and insulinaemic responses post-exercise between trials

Secondary Outcomes

  • Cognition(305 minutes)
  • Visual analogue scale (VSA)(305 minutes)
  • Substrate oxidation(305 minutes)
  • Inflammation(305 minutes)
  • Lipid profile(150 minutes)
  • Blood pressure(305 minutes)
  • Gut hormones(150 minutes)
  • Appetite(30 minutes)
  • Energy balance(480 minutes)

Study Sites (1)

Loading locations...

Similar Trials