Impact of Different Pre-exercise Breakfast Composition on Post-exercise Glycaemic Response, Appetite and Energy Balance
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Enrollment
- 12
- Locations
- 1
- Primary Endpoint
- Metabolic health
Study Overview
Brief Summary
This project aims to investigate the impact of acute bout of submaximal exercise under different pre-exercise dietary conditions (fasted state versus high carbohydrate breakfast versus high protein breakfast) on postprandial glycaemic, appetite regulation and energy balance.
Detailed Description
Participants will be asked to arrive to the laboratory between 08:00 and 9:00 am after not eating for between 12-14 hours i.e. in a fasted state (water intake is permitted and encouraged). Participants will then be given one of three test drinks (i.e., breakfast): 1) water only; 2) high carbohydrate drink; or 3) high protein (whey protein) drink. Each of these drinks will also contain 500 mL of water and artificial sweetener. 2 h after breakfast, participants will then exercise on a treadmill for 45 min followed by a 2-h oral glucose tolerance test (OGTT) and 30 min ad libitum lunch intake. Blood samples, blood pressures and questionnaire (e.g., appetite and mood) will be collected in a regular pattern throughout the trials. Cognitive functions will be tested at baseline, pre-exercise and 2 h post-exercise. Energy balance will be assessed using food diary and an accelerometer for the rest of the day after leaving the laboratory until midnight.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Basic Science
- Masking
- Double (Participant, Investigator)
Masking Description
Participants and Researchers will be blinded to the interventions.
Eligibility Criteria
- Ages
- 30 Years to 55 Years (Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Healthy physical active men (self-reported regular exercise at least 30 min moderate-intensity 3 times per week)
- •Aged between 30 to 55 years
- •Weight stable for more than 3 months (no change in weight +/- 3%)
- •Non-smoker
Exclusion Criteria
- •Personal history of/existing diabetes, cardiovascular disease, metabolic disease or dyslipidaemia
- •Taking medications that may influence lipid or carbohydrate metabolism or immune system function
- •Physically inactive
Arms & Interventions
Fasted exercise
Fasted prior to exercise
Intervention: Fasted exercise (Behavioral)
High protein breakfast exercise
High protein breakfast consumption prior to exercise
Intervention: High protein breakfast exercise (Behavioral)
High carbohydrate breakfast exercise
High carbohydrate breakfast consumption prior to exercise
Intervention: High carbohydrate breakfast exercise (Behavioral)
Outcomes
Primary Outcomes
Metabolic health
Time Frame: 150 minutes
Changes in blood glycaemic and insulinaemic responses post-exercise between trials
Secondary Outcomes
- Cognition(305 minutes)
- Visual analogue scale (VSA)(305 minutes)
- Substrate oxidation(305 minutes)
- Inflammation(305 minutes)
- Lipid profile(150 minutes)
- Blood pressure(305 minutes)
- Energy balance(480 minutes)
- Gut hormones(150 minutes)
- Appetite(30 minutes)
Investigators
Yung-Chih Chen
Principal Investigator
National Taiwan Normal University