To evaluate the efficacy of yapana basti(medicated enema) and nasya (nasal drops)along with shirobasti followed by kauncha paka in the management of kampavata with special reference to parkinson’s disease (pd)

Phase 2/3

Completed

• Conditions: Parkinsons disease. Ayurveda Condition: KAMPAH/VEPATHUH,

• Registration Number: CTRI/2022/06/043053
• Lead Sponsor: National Institute of Ayurveda

Brief Summary

Parkinson’s disease (PD) is a group of progressive neurodegenerative disorders characterized by tremor, akinesia, bradykinesia, muscular rigidity, abnormalities of posture, impairment of postural control and balance, abnormalities of gait, dysphonia, dysarthria and stammer.

In Ayurveda the Vata Dosha which is the motivator and controller of other two Doshai.e.,Pitta and Kapha, is responsible for almost all types of diseases. All motor and sensory functions are control by Vata Dosha. According the Ayurveda Major neurological problems come under Vata Vyadhi, Kampavata is one of them. Kampavata is that condition caused by Vata in which all the part of the body including the head will have tremors.

Ayurveda takes a unique approach to the management of Vata Vyadhi (Kampa vata/PD) with a special emphasis on eliminating their cause by Panchakarma. Panchakarma procedures like different types of Snehana, Swedana , Vamana, Virechana, Basti and Nasya Karma are especially indicated in the treatment of neurological diseases. Besides a special treatment like Shirobasti, Shirodhara, Nasya and Basti karma are indicated in such diseases.

GROUPING:- After the complete examination and investigation, all the 30 patients will be divided into two groups (15 patients in each group) detail as below-ï‚· Group A- Tritiya Baladi Yapana Basti along with Shirobasti for 16 days followed by Kauncha Paka 10 gm twice a day after meal for 15 days. ï‚· Group B- Nasya along with Shirobasti for 16 days followed by Kauncha Paka  10 gm twice a day after meal for 15 days.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-15
• Study Completion: 2023-08-14
• Last Update Posted: 2023-10-11

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Patients between 40-70 years of age.
• Patients with clinical signs and symptoms of Kampavata/ PD.
• Patients of either sex irrespective of their occupation, religion and socio-economic status.
• Patients of Kampavata/PD who are fit for Shirobasti , Basti and Nasya.
• Patients willing to participate for interventional study.

Exclusion Criteria

• Patients with severe systemic disorders as Uncontrolled Hypertension, Cardiac Problem, Uncontrolled Diabetes Mellitus, Tuberculosis, Leprosy, Paralysis, malignant disease etc.
• Patients unfit for Shirobasti , Basti and Nasya.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Assessment of changes will be assessed on the basis of UPDRS	Assessment will be done at | Day 0, Day 16, Day 31 and after follow-up of 15 days
(Unified Parkinson’s disease Rating Scale) (modified) before and after the treatment.	Assessment will be done at | Day 0, Day 16, Day 31 and after follow-up of 15 days

Secondary Outcome Measures

Name	Time	Method
Assessment of changes in following specific signs and symptoms of Kampavata	1 kampa

Trial Locations

Locations (1)

National Institute of Ayurveda; 🇮🇳 Jaipur, RAJASTHAN, India

National Institute of Ayurveda

🇮🇳Jaipur, RAJASTHAN, India

Dr Raj kumar Jha

Principal investigator

8432881200

drrajkumar.jha123@gmail.com