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临床试验/NCT07196982
NCT07196982已完成不适用

Risk Factors for Intertrochanteric Femoral Fractures With Concomitant Lateral Wall Involvement in Elderly Women

Second Affiliated Hospital of Soochow University1 个研究点 分布在 1 个国家目标入组 49 人开始时间: 2023年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
49
试验地点
1
主要终点
Association between Bone Mineral Density, BMI, and Lateral Wall Involvement in Intertrochanteric Femoral Fractures

研究概览

简要总结

This study aims to better understand the factors that increase the risk of a special type of hip fracture in older women, known as intertrochanteric femoral fractures with lateral wall involvement. Hip fractures are very common in elderly patients, especially in women after menopause, and can seriously affect independence, mobility, and quality of life.

Between January 2023 and February 2024, postmenopausal women who were admitted with intertrochanteric femoral fractures were studied. Among them, some patients had fractures only in the main hip area, while others had additional involvement of the lateral wall, an important supportive structure of the hip. Researchers collected information such as age, body mass index (BMI), bone mineral density (BMD), and bone metabolism markers.

The study found that women with lower BMI and lower bone mineral density at the hip and lumbar spine were more likely to have lateral wall involvement in their fractures. Age and blood markers of bone metabolism did not show a strong link.

Understanding these risk factors can help doctors improve preoperative evaluation, choose better surgical strategies, and recommend preventive measures such as bone health management and fall prevention. This may ultimately reduce complications, improve recovery, and support better long-term outcomes for elderly women with hip fractures.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
65 Years 至 85 Years(Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Postmenopausal women diagnosed with intertrochanteric femoral fractures.
  • •History of low-energy trauma (e.g., fall from standing height).
  • •Treated surgically with proximal femoral nail antirotation (PFNA) device, with or without lateral wall plate fixation.
  • •Availability of complete demographic and clinical data (age, height, weight, bone mineral density, and bone turnover markers).
  • •Eligible for retrospective case-control analysis.

排除标准

  • •High-energy trauma (e.g., motor vehicle accidents).
  • •Severe systemic comorbidities such as hepatic or renal failure, bone tumors, or endocrine disorders (e.g., hyperparathyroidism).
  • •Use of medications affecting bone metabolism within 6 months before surgery.
  • •Diagnosis of diabetes mellitus.
  • •History of chronic smoking or alcohol abuse.
  • •Inability to provide accurate anthropometric data (height and weight).

结局指标

主要结局

Association between Bone Mineral Density, BMI, and Lateral Wall Involvement in Intertrochanteric Femoral Fractures

时间窗: From hospital admission to postoperative BMD assessment (within 3 months of injury)

The primary outcome is to determine whether reduced bone mineral density (BMD) and lower body mass index (BMI) are independent risk factors for lateral wall involvement in elderly women with intertrochanteric femoral fractures. Measurements include lumbar spine and hip BMD assessed by dual-energy X-ray absorptiometry (DXA) and BMI calculated from height and weight. Logistic regression analysis is used to evaluate associations between these factors and the presence of lateral wall fractures.

次要结局

未报告次要终点

研究者

发起方
Second Affiliated Hospital of Soochow University
申办方类型
Other
责任方
Sponsor

研究点 (1)

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