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myDiabby Healthcare vs Diary in Gestational Diabetes Mellitus.

Completed
Conditions
Gestational Diabetes
Interventions
Other: Treated group
Other: Control group
Registration Number
NCT05510583
Lead Sponsor
Hôpital NOVO
Brief Summary

The purpose of the study is to demonstrate the non-inferiority of the onset of maternal, foetal, and neonatal complications for patients who had Gestational diabetes mellitus (GDM) and who had been monitored by myDiabby Healthcare compared to patients who had a classic glycemic blood monitoring by diary

Detailed Description

TELESUR-GDM is a descriptive and comparative study which will be compared to ERD2 study. ERD2 (personal data) was a retrospective study leaded in Rene Dubos hospital. The primary objective was to evaluate de proportion of patients who had a blood screening for type 2 diabetes after having a gestational diabetes and who gave birth between 2013 and 2015 in Rene Dubos hospital. The primary outcome was the discovery of a diabetes after the OGTT test (75g of glucose), 2 to 3 months after delivery, a fasting blood glucose rate ≥ 1,26 g/L and a plasma glucose after 2 hours ≥ 2g/L

* In ERD2 study 391 subjects were included. The patients were over 18 years old and had a gestational diabetes and were informed by a survey. The main criteria of maternal and neonatal complications were a maternal high blood pressure, a neonatal jaundice, neonatal hypocalcemia and hypoglycemia, and shoulders dystocia. In this study the patients were followed up with classic diary for glycemic blood rate.

* With TELESUR-GDM study, the objective is to prove the non-inferiority of the new method of monitoring for blood glucose rate (myDiabby Healthcare) for patients who had a gestational diabetes and who gave birth between 01/01/2021 and the 31/12/2021. The data will be collected with an informatic secured data base.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
668
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Group 2Treated groupPregnant women (≥18 years) with gestational diabetes who gave birth between 01/01/2021 and 31/12/2021. Patients received remote monitoring with myDiabby Healthcare
Group 1Control groupPregnant women (≥18 years) with gestational diabetes who gave birth between 01/01/2013 and 30/06/2015. Patients received traditional paper-based blood glucose monitoring.
Primary Outcome Measures
NameTimeMethod
Assessment of the non-inferiority of the occurrence of maternal, fetal, and neonatal complications for patients of both groupsAt the end of the Study, an average of 8 month

Comparison, for patients with GDM, of the composite score (maternal / foetal - neonatal) between the group with remote monitoring by the myDiabby Healthcare and the group of patients with traditional monitoring (paper glycemic diaries). For each item answered "yes" count 1 point and "no" count 0 point.

For information, the composite score is based on the following items:

Maternal :

* High blood pressure (≥140/90 mmHG)

* Caesarean section

* Instrumental extraction

* Perineal Trauma : complete or complicated perineal tearing

* Pre-eclampsia

Foetal and neonatal :

* birth weight ≥ 95th percentile for gestational age (neonatal macrosomia)

* intrauterine growth restriction (birth weight ≤ 5th percentile)

* APGAR \< 7 at 5 minutes

* Fetal death in utero

* Neonatal hypoglycemia

* Neonatal hypocalcemia

* Neonatal acidosis : pH\<7,10 and lactate \>6µmol

* Shoulders dystocia

* Collarbone fracture, brachial plexus

* Neonatal jaundice

Secondary Outcome Measures
NameTimeMethod
Comparison of the rate of patients put on insulin in both groupsAt the end of the Study, an average of 8 month

Number of patients put on insulin in each group and comparison.

Comparison, for each maternal and each Foetal/Neonatal composite items, between both groupsAt the end of the Study, an average of 8 month

Prevalence of each maternal and each Foetal/Neonatal composite item in each group. For each item answered "yes" count 1 point and "no" count 0 point

For information, the maternal composite items are as follows:

* High blood pressure (≥140/90 mmHG)

* Hospitalization during pregnancy

* Caesarean section

* Instrumental extraction

* Perineal Trauma : complete or complicated perineal tearing

* Pre-eclampsia

For information, the Foetal/Neonatal composite items are as follows:

* birth weight ≥ 95th percentile for gestational age (neonatal macrosomia)

* intrauterine growth restriction (birth weight ≤ 5th percentile)

* APGAR \<7 at 5 minutes

* Fetal death in utero

* Neonatal hypoglycemia

* Neonatal hypocalcemia

* Neonatal acidosis : pH\<7,10 and lactate \>6µmol

* Shoulders dystocia

* Collarbone fracture, brachial plexus

* Neonatal jaundice

Trial Locations

Locations (1)

Endocrinology department - Centre Hospitalier René Dubos

🇫🇷

Pontoise, France

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