Buprenorphine for Prisoners
Overview
- Phase
- Phase 3
- Intervention
- Buprenorphine +OTP
- Conditions
- Heroin Addiction
- Sponsor
- Friends Research Institute, Inc.
- Enrollment
- 213
- Locations
- 2
- Primary Endpoint
- Number of Days of Heroin Use
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
This five-year study examines the effectiveness of buprenorphine treatment provided to previously-addicted inmates(N=320; 160 males, 160 females) initiated in prison and continued in the community. The study also examines the extent to which the setting of post-release buprenorphine is provided.It is expected that participants receiving in-prison buprenorphine will have superior outcomes compared to participants who did not receive in-prison buprenorphine.
Detailed Description
Participants will be randomly assigned, within gender, to one of four treatment conditions: 1) buprenorphine and counseling in prison, with referral for continued treatment at an OTP upon release; 2) buprenorphine and counseling in prison, with referral for continued treatment at a CHC upon release; 3) counseling only in prison, with referral for buprenorphine and counseling at a OTP upon release; and 4) counseling only in prison, with referral for buprenorphine and counseling at a CHC upon release. Participants will be assessed at study entry and at 1, 3, 6, and 12 months following their release from prison. Outcome measures include: treatment entry and retention in the community, heroin use, cocaine use, HIV infection, HIV-risk behaviors, criminal activity, and employment.
Investigators
Eligibility Criteria
Inclusion Criteria
- •pre-release prison inmate with 3-6 months remaining until planned release
- •history of heroin dependence(meeting DSM-IV criteria of heroin dependence at the time of incarceration and manifesting physical dependence during the year preceding incarceration
- •suitability for buprenorphine treatment as determined by medical evaluation
- •willingness to participate in the study
- •having a Baltimore address and planning to live in Baltimore after release from prison -
Exclusion Criteria
- •evidence of kidney failure
- •evidence of liver failure
- •history of psychosis
- •having a pending parole hearing
- •unadjudicated charges that could result in additional prison time or transfer to another facility -
Arms & Interventions
Buprenorphine+OTP
Buprenorphine and counseling in prison and continued at opioid treatment program (OTP) upon release.
Intervention: Buprenorphine +OTP
Buprenorphine+CHC
Buprenorphine and counseling in prison and continued at a community health center (CHC) upon release.
Intervention: Buprenorphine +CHC
Counseling + OTP
Counseling only in prison and Buprenorphine upon release at a opioid treatment program (OTP)
Intervention: Counseling +OTP
Counseling + CHC
Counseling only in prisons and Buprenorphine upon release at a community health center (CHC)
Intervention: Counseling +CHC
Outcomes
Primary Outcomes
Number of Days of Heroin Use
Time Frame: 1 year
mean days used heroin during the past 30 days
Drug Abuse Treatment Entry and Retention in the Community
Time Frame: 1 year
entered community treatment within 10 days of release from prison (yes vs. no)
Secondary Outcomes
- Criminal Activity(1 year)
- Employment Status(1 year)
- HIV Risk Behavior Needle Sharing(1 year)
- Number of Days of Cocaine Use(1 year)
- HIV Risk Behavior(1 year)