CTRI/2022/02/040457
Recruiting
未知
A study to define Epigenetic signatures and gut microbiome profiles in Autism Spectrum Disorders (ASD) and assessment of clinical outcomes of Fecal Microbiota Transfer Therapy (FMT) in ASD and investigate the causal association between gut microbiome and development of ASD (Gut Symbiont Restoration Therapy - GSRT)
Providence Microbiome Research Center Private Limited0 sites0 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Providence Microbiome Research Center Private Limited
- Status
- Recruiting
- Last Updated
- 3 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •DONOR INCLUSION CRITERIA
- •1\. Both parents of the donors are willing to provide Audio\-Video and a written informed consent form.
- •2\. Healthy neurotypical children.
- •3\. Healthy donors, both boys and girls, inclusive of age 3 to 12 years.
- •4\. Children with the same blood group, preferably the same gender, are selected.
- •5\. No abnormalities in serological testing.
- •6\. No family history of metabolic disorders and autoimmune diseases and cancers Etc.
- •7\. No history of usage of antibiotics, antifungals, antivirals, and immunosuppressant in the last three months.
- •8\. No gastrointestinal conditions like a history of IBD, IBS, chronic constipation, chronic diarrhea and Celiac disease.
- •9\. No active illness.
Exclusion Criteria
- •DONOR EXCLUSION CRITERIA
- •1\. Adults, adolescents and children less than 3 yrs.
- •2\. Any abnormality on serological testing.
- •3\. Any illness acute or chronic.
- •4\. Any family history of metabolic syndrome, chronic illness, autoimmune diseases, cancer and mental illness Etc.
- •RECIPIENT EXCLUSION CRITERIA
- •1\. Abnormal karyotyping.
- •2\. Syndrome patients.
- •3\. Cerebral palsy, mental retardation, and global developmental delay
- •4\. Known genetic disorders.
Outcomes
Primary Outcomes
Not specified
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