Comparison of CTI Ablation Prior to or After LA Ablation for AF

Phase 3

Completed

• Conditions: Atrial Fibrillation
• Interventions: Procedure: CTI ablation Timing

• Registration Number: NCT02325778
• Lead Sponsor: NYU Langone Health

Brief Summary

This study is designed to determine if CTI prior to CPVA/PVI/Linear Lesions/Fractionation results in reduced left atrial ablation lesion sets prior to restoration of sinus rhythm in patients with long standing persistent atrial fibrillation in the absence of antiarrhythmic drug therapy compared to CTI after CPVA/PVI/Linear Lesions/Fractionation.

Detailed Description

Not available

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2014-12-16
• Study First Submitted QC: 2014-12-24
• Study First Posted: 2014-12-25
• Primary Completion: 2016-07
• Status Verified: 2016-08
• Last Update Submitted: 2016-08-04
• Last Update Posted: 2016-08-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

• continuous/persistent atrial fibrillation

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Exclusion Criteria

• age<18
• congenital heart disease
• pacemaker or ICD implant
• previous ablation

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
CTI First	CTI ablation Timing	CTI ablation prior to left atrial ablation
CTI second	CTI ablation Timing	CTI ablation after left atrial ablation

Primary Outcome Measures

Name	Time	Method
Number of Ablation Lines Required to Organize Atrial Fibrillation to an Atrial Tachycardia or Sinus Rhythm	Acute (intra procedure)

Secondary Outcome Measures

Name	Time	Method
Early recurrence of atrial arrhythmias	3 months	Atrial Fibrillation or Atrial Tachycardia lasting longer than 30 seconds

Trial Locations

Locations (1)

NYU Langone Medical Center; 🇺🇸 New York, New York, United States