Postoperative quadriceps strength of continuous femoral ropivacaine or levobupivacaine: a prospective, randomized double-blind trial after total knee arthroplasty
Phase 3
- Conditions
- Patients scheduled for elective unilateral total knee arthroplasty under general anesthesia and peripheral nerve block
- Registration Number
- JPRN-UMIN000008840
- Lead Sponsor
- Department of Anesthesia and Intensive Care Medicine, Osaka University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Not provided
Exclusion Criteria
1.Inability to communicate lucidly 2.Bilateral TKA 3.revision knee arthroplasty 4.Under 20 years old 5.Allergy to any of the drugs used in this study 6.ASA-PS > III 7.Chronic opioid use 8.Diabetes mellitus with sensory disorders 9.Neurological disability 10.Infections around femoral crease 11.Platelet < 5.0 * 10^4 /mcl 12.Pregnancy, possibility of pregnancy, or breast-feeding women 13.Contraindications to peripheral nerve blocks
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary endpoint is the difference in maximum voluntary isometric contraction (MVIC) of the quadriceps 48 hours after surgery compared with the preoperative MVIC, expressed as a percentage of the preoperative MVIC.
- Secondary Outcome Measures
Name Time Method Secondary endpoints included postoperative knee range-of-motion, ambulatory ability, pain scores(Visual Analog Scale) at rest and during knee movement, and the consumption of additional analgesics.