Investigation of the effect of Plantago major, and Rheum on colitis

Phase 3

• Conditions: lcerative colitis.; Ulcerative colitis

• Registration Number: IRCT20150927024228N5
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 January 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Patients aged 18 to 60 with mild and moderate ulcerative colitis confirmed by endoscopy and biopsy and diagnosed by a gastroenterologist who signed the informed consent form and did not meet the exclusion criteria.

Exclusion Criteria

Pregnancy or breastfeeding
Taking antibiotics
Taking herbal medicines, NSAIDs, OCPs or hormone therapy (in the last 2 weeks)
Complications of the disease (such as massive bleeding requiring hospitalization or emergency surgery, fulminant colitis, peritonitis, toxic megacolon, obstructive stenosis),
Suffering from liver, kidney, heart, cancer or celiac disease at the same time
Addiction to smoking or drugs
Suffering from other autoimmune diseases

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Partial Mayo score. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: Partial Mayo score questionnaire.

Secondary Outcome Measures

Name	Time	Method
Quality of life. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: Quality of life questionnaire (IBDQ-9).;Anxiety, stress, and depression. Timepoint: At the beginning of the study, 3, 6 and 10 weeks. Method of measurement: DASS-21 questionnaire.