Preoperative Dexamethasone Enhances Quality of Recovery After Laparoscopic Bariatric Surgery: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Global Quality of Recovery (QoR-40) score in the first 24 hours after surgery
研究概览
简要总结
In the obese patient, adequate pain relief in the postoperative period is an important parameter that affects patient comfort and hospital stay. Increasing patient comfort and recovery quality can be achieved by avoiding undesirable effects such as nausea and vomiting, as well as analgesia. In our study, our aim is to evaluate the effect of dexamethasone added to multimodal analgesia on postoperative patient comfort in the obese patient group with a 40-item scale.
详细描述
Postoperative pain prolongs hospital stay, delays wound healing, increases infection rates, and increases the incidence of drug side effects due to the use of systemic pain relievers (especially opioids).
Good pain control facilitates respiratory effort, allows the patient to perform respiratory exercises and cough to correct the increased thoracic fat mass and impaired respiratory mechanics due to anesthesia. The patient without pain is mobilized early and discharged early.
Our aim is to evaluate the effect of dexamethasone added to multimodal analgesia on postoperative patient comfort in the obese patient group with a 40-item scale.
Patients will be divided in to two groups (group D and group C):
Group D (Dexamethasone Group):
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Body mass index>30 kg/m2
- •The American Society of Anaesthesiologists (ASA) physical status class I, II
- •The American Society of Anaesthesiologists (ASA) physical status class III only because of morbid obesity
- •Patients who will undergo an elective laparoscopic sleeve gastrectomy (LSG)
- •Those who are literate enough to answer the compilation quality score (QoR-40) questionnaire
排除标准
- •refusal to participate
- •allergy to the study drugs
- •chronic kidney disease (creatinine>150 μmol/L)
- •mental illness
- •liver, respiratory or oncological disease,
- •cardiac dysfunction (ejection fraction <40%),
- •uncontrolled hypertension,
- •preoperative analgesic use,
- •chronic pain,
- •history of alcohol or drug addiction
研究组 & 干预措施
Group D
Patients who used/applied dexamethasone before bariatric surgery were included in this group.
干预措施: Group D (Drug)
Group C
Patients who did not use dexamethasone or steroid-derived drugs were included in this group.
干预措施: Group C (Drug)
结局指标
主要结局
Global Quality of Recovery (QoR-40) score in the first 24 hours after surgery
时间窗: postoperative day 1
The recovery quality of the patients 24 hours after the operation will be evaluated with the QoR-40 questionnaire. The questionnaire consists of 40 questions that examine five domains of patient recovery using a five point Likert scale: none of the time, some of the time, usually, most of the time, and all of the time. The five domains include physical comfort, pain, physical independence, psychological support, and emotional state. As a result of the evaluation, the total score ranges from 40 (worst review quality score) to 200 (best review quality score).
The score for each of the five parameters that make up the QoR-40 questionnaire
时间窗: postoperative day 1
It consists of 5 parameters: physical independence score (n = 5), patient support score (n = 7), Physical comfort score (n = 12), emotional state score (n = 9) and pain score (n = 7).
次要结局
- Morphine consumption in the first 24 hours after surgery(postoperative day 1)
- The incidences of post-operative nausea and vomiting (PONV)(postoperative day 1)
- Time to first mobilization(Up to 24 hours after surgery.)
- Time to discharge(Trough hospital stay, an average of 1 week)
研究者
Yasemin Burcu Ustun
Professor
Ondokuz Mayıs University