NL-OMON22304招募中不适用
ACTION-1: ACT guided heparinization during open abdominal aortic aneurysm (AAA) repair, a randomised trial.
Dijklander Ziekenhuis in collaboration with Amsterdam UMC, location VUmc and AMC0 个研究点目标入组 750 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 750
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •Able to speak and read in local language of trial hospital.
- •Patients older than 18 years scheduled for elective, open repair of an iliac or abdominal aortic aneurysm distal of the SMA (DSAA segment C).
- •Implantation of a tube or bifurcation prosthesis.
- •Trans-abdominal or retroperitoneal surgical approach of aneurysm.
- •Able and willing to provide written informed consent.
排除标准
- •Not able to provide written informed consent.
- •Previous open or endovascular intervention on the abdominal aorta (previous surgery on other parts of the aorta or iliac arteries is not an exclusion criterion).
- •History of coagulation disorders, heparin induced thrombocytopenia (HIT), allergy for heparin or thrombocyte pathology.
- •Impaired renal function with EGFR below 30 ml/min.
- •Acute open AAA surgery.
- •Hybrid interventions.
- •Connective tissue disorders.
- •Dual anti-platelet therapy, which cannot be discontinued.
- •Life expectancy less than 2 years.
- •Inflammatory, mycotic or infected aneurysms
- •Allergy for protamine or fish protein
研究者
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