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Clinical Trials/NCT03894293
NCT03894293
Unknown
N/A

Correlations Among Functional Performance, Muscle Strength and Weaning Rate in Mechanically Ventilated Patients

Taipei Veterans General Hospital, Taiwan1 site in 1 country50 target enrollmentFebruary 20, 2019

Overview

Phase
N/A
Intervention
Not specified
Conditions
Respiratory Failure
Sponsor
Taipei Veterans General Hospital, Taiwan
Enrollment
50
Locations
1
Primary Endpoint
Correlations between the Change from Baseline 'Functional Status Score for the ICU (FSS-ICU)' to the timing before weaning and the ventilator days
Last Updated
7 years ago

Overview

Brief Summary

To assess the correlations among the physical functional performance, muscle strength, respiratory muscle strength and the ventilator weaning rate.

Detailed Description

To assess the correlations among the physical functional performance, muscle strength, respiratory muscle strength and the ventilator weaning rate. Investigators use the DEMMI and FSS-ICU to evaluation the physical functional performance. And MRC score and hand dynamometer to record the muscle strength. The weaning parameters include Pi, PE, RSI,minute ventilation, tidal volume and cuff leak will be recorded. After the participant enters the Respiration Care Center, Doctor and physical therapist evaluate the consciousness and meet the inclusion criteria and the participant will received the first evaluation. The second evaluation will be held before the ventilator weaning timing.

Registry
clinicaltrials.gov
Start Date
February 20, 2019
End Date
February 19, 2020
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • respiratory failure with mechanical ventilator use
  • 48 hours after transferring to respiratory care center
  • consciousness clear and can obey orders
  • vital signs stable

Exclusion Criteria

  • conscious disturbance
  • neuromuscular disease
  • patho fracture

Outcomes

Primary Outcomes

Correlations between the Change from Baseline 'Functional Status Score for the ICU (FSS-ICU)' to the timing before weaning and the ventilator days

Time Frame: from baselineto the timing before weaning

Correlations between the Functional physical performance and the ventilator days.It contains 5 items including rolling, supine-to-sit, unsupported sit, sit-to-stand and ambulation. The scores of 5 items range from 0 to 7. 0 means unable to perform; 1 means total assistance; 2 means maximum assistance; 3 means moderate assistance; 4means minimal assistance; 5 means supervision; 6 means moderate independence and 7 means complete independence. The total score ranges from 0 to 35. Higher values represent better functional performance.

correlations between the Change from Baseline 'de Morton Mobility Index (DEMMI)' to the timing before weaning and the ventilator days

Time Frame: from baselineto the timing before weaning

Correlations between the Functional physical performance and the ventilator days.It contains 5 items including bed skill, chair skills, static balance, walking and dynamic balance. The scores of 'bed', 'chair', 'static balance', 'walking' range from 0 to 4. And the score of 'dynamic balance' range from o to 3. The sum of 5 items is total raw score. Total Raw score is 0 to 19. And raw score can be converted to DEMMI score, ranging from 0 to 100. Higher values represent better mobility performance.

Secondary Outcomes

  • Correlations between the Change from Baseline 'grip - hand strength' to the timing before weaning and ventilator days(from baselineto the timing before weaning)
  • Correlations between the Change from Baseline 'Maximal inspiration pressure(PI)' to the timing before weaning and ventilator days(from baselineto the timing before weaning)
  • Correlation between the Change from Baseline 'Medical Research Council (MRC) scale' to the timing before weaning and ventilator days(baseline, before weaning)
  • Correlation between the Change from Baseline 'Maximal expiration pressure(PE)' to the timing before weaning and ventilator days(from baselineto the timing before weaning)

Study Sites (1)

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