Study Project Comparing the Sequelae of COVID-19 Infection in Patients Who Have and Have Not Received Ventilatory Support in Critical Care

Assistance Publique - Hôpitaux de Paris1 site in 1 country478 target enrollmentJune 1, 2020

Overview

Brief Summary

To assess the proportion of post-intensive care syndrome (PICS) of patients who received high flow humidified oxygen with FiO2 ≥50% for more than 48h and / or who received mechanical ventilation for more than 48h in a context of hospitalization in intensive care for COVID-19 pneumonia

Registry

clinicaltrials.gov

Start Date

June 1, 2020

End Date

October 1, 2020

Last Updated

5 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

Assistance Publique - Hôpitaux de Paris

Responsible Party

Sponsor

Eligibility Criteria

Inclusion Criteria

•Group 1: patients hospitalized in intensive care units for ARDS with SARS-CoV-2
•Admitted between March 1 and May 10, 2020 in one of the sectors of the Bicêtre hospital approved for critical care
•proven SARS-CoV-2 infection
•Treated by invasive mechanical ventilation or high flow humidified oxygen with FiO2 ≥50% for more than 48 hours.
•Group 2: patients hospitalized outside intensive care units
•Admitted between March 1 and May 10, 2020 in an area of Bicêtre hospital having cared for patients infected with SARS-CoV-2 excluding critical care: pulmonology, internal medicine / orthopedics, infectious diseases, nephrology , acute geriatrics, neurology.

Exclusion Criteria

•Patients having refused the post consultation at 3 month
•Without social security coverage

Outcomes

Primary Outcomes

post-intensive care syndrome (PICS)

Time Frame: 3 month after hospitalisation

To assess the proportion of post-intensive care syndrome (PICS) of patients who received high flow humidified oxygen with FiO2 ≥50% for more than 48h and / or who received mechanical ventilation for more than 48h in a context of hospitalization in intensive care for COVID-19 pneumonia.

Secondary Outcomes

Evaluate the 3-month mortality of patients released alive from intensive care(3 month after end of hospitalisation)
Describe the overall state of health and the main organ sequelae of these patients(3 month after hospitalisation)
functional respiratory sequelae(3 month after hospitalisation)