Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Home Mechanical Ventilation
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
- Enrollment
- 55
- Locations
- 1
- Primary Endpoint
- Time to first ICU admission
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular disease's population.
Detailed Description
Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficacy is mostly assessed by daytime blood gases and nocturnal oxymetry (SpO2). Transcutaneous CO2 measure (TcCO2) has shown higher sensitivity than SpO2 to detect hypoventilation in neuromuscular diseases (NMD) patients. No data exist on the prognostic value of these techniques to monitor mechanical ventilated NMD patients. Basing on retrospective data review, investigators aimed to compare the prognostic value of the data obtained using different tools to assess residual hypoventilation in the cohort of ventilated NMD patients followed at our reference center.
Investigators
Eligibility Criteria
Inclusion Criteria
- •neuromuscular disease
- •age ≥18 years
- •mechanically ventilated
- •capno-oxymetry performed between 2009 and 2011
Exclusion Criteria
- •Long-term oxygen therapy
Outcomes
Primary Outcomes
Time to first ICU admission
Time Frame: 6 years
Time to first ICU admission
Secondary Outcomes
- Mortality(6 years)