Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients
- Conditions
- Home Mechanical VentilationNeuromuscular Disease
- Registration Number
- NCT02551406
- Lead Sponsor
- Centre d'Investigation Clinique et Technologique 805
- Brief Summary
Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular disease's population.
- Detailed Description
Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficacy is mostly assessed by daytime blood gases and nocturnal oxymetry (SpO2). Transcutaneous CO2 measure (TcCO2) has shown higher sensitivity than SpO2 to detect hypoventilation in neuromuscular diseases (NMD) patients. No data exist on the prognostic value of these techniques to monitor mechanical ventilated NMD patients.
Basing on retrospective data review, investigators aimed to compare the prognostic value of the data obtained using different tools to assess residual hypoventilation in the cohort of ventilated NMD patients followed at our reference center.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
- neuromuscular disease
- age ≥18 years
- mechanically ventilated
- capno-oxymetry performed between 2009 and 2011
- Long-term oxygen therapy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Time to first ICU admission 6 years Time to first ICU admission
- Secondary Outcome Measures
Name Time Method Mortality 6 years Time to death
Trial Locations
- Locations (1)
Hopital Raymond Poincare
🇫🇷Garches, France