JPRN-UMIN000010091已完成4 期
A prospective randomized clinical trial, the effect of long acting CCBs in post-acute myocardial infarction patients - ACROSS-AMI (ACh-induced Coronary Spasm Study - Nifedipine and Benidipine After Acute Myocardial Infarction)
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University0 个研究点目标入组 97 人开始时间: 2013年2月21日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 97
研究概览
简要总结
There were no significant differences in the baseline clinical characteristics except younger age in nifedipine compared with benidipine groups. In age-adjusted model, the difference of dilator response to ISDN between initial and follow-up ACh tests was almost identical between 2 groups. However, the difference of constrictor response to ACh was significantly improved in the nifedipine rather than benidipine groups.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20years-old 至 85years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •Patients with 1) Unstable angina (UAP) 2) Triple vessel disease 3) Left ventricular ejection fraction <40% 4) Chronic atrial fibrillation 5) Severe hepatic dysfunction 6) Low tolerability of DHP-CCB 7) A history of DES implantation 8) Patients who were recognized by the chief physician to be inappropriate for study participation
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