MedPath

A prospective randomized clinical trial, the effect of long acting CCBs in post-acute myocardial infarction patients

Phase 4
Conditions
ST-segment elevation myocardial infarction(STEMI) or non-ST elevation myocardial infarction(NSTEMI)
Registration Number
JPRN-UMIN000010091
Lead Sponsor
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
Brief Summary

There were no significant differences in the baseline clinical characteristics except younger age in nifedipine compared with benidipine groups. In age-adjusted model, the difference of dilator response to ISDN between initial and follow-up ACh tests was almost identical between 2 groups. However, the difference of constrictor response to ACh was significantly improved in the nifedipine rather than benidipine groups.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
97
Inclusion Criteria

Not provided

Exclusion Criteria

Patients with 1) Unstable angina (UAP) 2) Triple vessel disease 3) Left ventricular ejection fraction <40% 4) Chronic atrial fibrillation 5) Severe hepatic dysfunction 6) Low tolerability of DHP-CCB 7) A history of DES implantation 8) Patients who were recognized by the chief physician to be inappropriate for study participation

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
© Copyright 2025. All Rights Reserved by MedPath