The Standardized and Economical Mode for the Prevention and Management of Chronic Cardiovascular Diseases: Matrix System From Rural Shaanxi ( MATRIX ) Ⅰ
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,210
- 试验地点
- 1
- 主要终点
- the improvement of control rate of hypertension with low-cost in rural Shaanxi
研究概览
简要总结
The purpose of the study is to build a prevention and management system of hypertension in rural Shaanxi, China, which tries to use the standardized and economical methods to improve the outcome of chronic cardiovascular diseases.
详细描述
Hypertension is common in China, but there are low rates of awareness (36.0%), treatment (22.9%) and control (5.7%) in the hypertension population of an estimated 200 million adults, a figure generated from the nationwide China Patient-Centered Evaluative Assessment of Cardiac Events (PEACE) Million Person Project (MPP) . Substantial health and economic burdens are caused by hypertension, and adequate control of blood pressure (BP) has been a national public health priority. In China, nearly half of population are living in rural areas , where lower treatment and control rates of hypertension compared with urban areas. Expenditure of antihypertension medications and insufficient professional ability of rural doctors were the major problems facing hypertension management in rural areas of China with backward economies.
Absence of affordable medications prescribed may be a major barrier to adherence to medications. The rural doctors with insufficient professional ability had not to provide standard management of hypertension. So, an effective, cheap and simple hypertension control strategy was urgently needed in underdeveloped rural areas.
My center has been devoted to the study of hypertension in economically backward rural areas of Shaanxi Province in Western China for decades. We provided a cheap and simple hypertension management plan suitable for these areas. Because the cost of the management was about $10 dollars per year, the plan was called the ten dollars project (TDP). The TDP included a management system and a cheap treatment plan. The management software for hypertension was designed to help rural doctors with poor professional medical ability standardly manage hypertension adhering to the guidelines. Of course, a more effective and affordable treatment costing about ten dollars a year is the core of this system. The aim of this study was to measure whether the TDP can effectively improve the control of hypertension in rural areas.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •primary hypertension;
- •Age ≥ 18 years old;
排除标准
- •Secondary hypertension;
- •the acute onset of cardiovascular events within three months;
- •severe liver disease (ALT increased 2-fold greater than creatinine 2.5mg/dl);
- •Severe cardiomyopathy, congenital heart disease, rheumatic heart disease
- •malignancies
- •allergic to study drugs
- •with clear contraindications on study drugs
研究组 & 干预措施
Treatment with Ten Dollars Project (TDP)
Hypertension of patients in the TDP group were managed with the protocol of "Ten Dollars Project (TDP)" by doctors in village clinic.
干预措施: Hydrochlorothiazide, Captopril, Nitrendipine, Aspirin (Drug)
结局指标
主要结局
the improvement of control rate of hypertension with low-cost in rural Shaanxi
时间窗: Patients in the TDP group accepted protocol of TDP to manage hypertension and patients in the control group were managed by the original protocol for six months. Compare the change of control rate at baseline and the end of the sixth month.
value whether the protocol of TDP could improve the control rate of hypertension in rural Shaanxi
次要结局
未报告次要终点
研究者
Hongyan Tian
vice director
First Affiliated Hospital Xi'an Jiaotong University