Comparison of single shot adductor canal block versus continuous adductor canal block for pain management in total knee arthroplasty a randomized control trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- 6. Timing of breakthrough medication (IV paracetamol)
研究概览
简要总结
AIM : To study and comparethe effectiveness of Multimodal Perioperative analgesia regime in pain management and earlyrehabilitation following total knee arthroplasty.
1.Single injection Adductor Canal Block +Infiltration of LA- iPAC (interspace b/w popliteal artery and capsule of posterior knee)
2.Single injection Adductor Canal Block
3.Continuous Adductor Canal Block WithCatheter.
HYPOTHESIS
Superiorityof catheter technique or iPAC + single inj.ACB over single injection adductor canal block in terms ofpostoperative analgesia , mobilization , early functional recovery and time todischarge
ACB:20 ml of 0.2% Ropivacaine
iPAC : 20 ml of 0.2 % Ropivacaine
CACB : 20 ml 0.2 % Ropivacaine through catheter infusion @ 6 ml / hr .
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 45.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients scheduled to undergo unilateral TKA under spinal anaesthesia .
排除标准
- •Bilateral Epidural / GA Creatinine > 1.2 , renal or hepatic dysfunction.
- •Allergic to any study medication , chronic opiod use , BMI >40 Chronic pain unrelated to knee joint.
结局指标
主要结局
6. Timing of breakthrough medication (IV paracetamol)
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
7. Length of stay
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
1.Pain Score : VAS (Visual Analog Score)
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
2. Knee ROM.
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
3. Ambulation distance
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents)
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
5. Anti Emetics usage
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
8. Discharge day
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
9. Patient satisfaction.
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
10. Active Quadriceps holding time
时间窗: 1.Pain Score : VAS (Visual Analog Score) | 2. Knee ROM. | 3. Ambulation distance | 4 .Opiate Consumption at 12 ,24,48 hrs.( calculation in morphine equivalents) | 5. Anti Emetics usage | 6. Timing of breakthrough medication (IV paracetamol) | 7. Length of stay | 8. Discharge day | 9. Patient satisfaction. | 10. Active Quadriceps holding time
次要结局
未报告次要终点