eural responses following transcranial magnetic stimulation (rTMS) in major depression - Neural responses following rTMS in MDD

Murai Toshiya0 个研究点目标入组 43 人开始时间: 2019年1月29日最近更新: 2023年10月17日

试验速览

High frequency rTMS for the left dorsolateral prefrontal cortex suggests improvement in depressive symptoms.

•1. Aged 20-75 years-old, male and female
•2. Diagnosis of major depressive disorder or bipolar II disorder
•3. Current diagnosis of major depressive episode
•4. HAMD_17 >=14 or BDI >=20
•5. resistent to medication (including medication intolerance)
•6. Capability of informed consent
•Healthy controls
•1. Aged 20-75 years-old, male and female without psychiatric disorder
•2. No family history of major depressive disorder and bipolar disorder in their first relatives
•3. Capability of informed consent

•Patients and healthy controls
•1. Implanted cardiac pacemaker
•2. Surgical aneurysm clips
•3. Neurostimulator
•4. Implanted pumps
•5. Metal fragments in body
•6. Subjects who are contraindicated for the use of MRI [e.g. Tattoos, permanent eyeliner (if ink contains metallic specks)]
•7. Diagnosis of neurological disorders (including epilepsy), substance dependence, or current serious medical illness (e.g. severe cardiac disease)
•8. History of neurological disorders (including epilepsy), substance dependence, or head injury with loss of consciousness
•9. Subjects with pregnancy or during lactation.
•10. Subjects who are judged as unsuitable for participation in this study

发起方

Murai Toshiya