Autologous punch grafting in vitiligo patients: the effect of punchdepth and punchsize - Punch grafting techniques in vitiligo

Academisch Medisch Centrum0 个研究点目标入组 35 人开始时间: 待定最近更新: 2024年4月29日

适应症

试验速览

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•-Patients with non-segmental and segmental vitiligo under medical treatment at the Netherlands Institute for Pigment Disorders
•-Age between 18 and 60 years
•-Patient is willing and able to give written informed consent
•-Vitiligo stable since 12 months without systemic therapy or 6 months without topical therapy as defined by the absence of new lesions and/or enlargement of existing lesions.
•-Vitiligo lesions on the extremities or trunk larger than 5x5cm

•-UV therapy or systemic immunosuppressive treatment during the last 12 months
•-Local treatment of vitiligo during the last 6 months
•-Vitiligo lesions with folliculair or non-folliculair repigmentations
•-Skin type 1
•-Hypertrophic scars
•-Cardial insufficiency
•-Patients with a history of hypersensitivity to (UVB) light and allergy to local anesthesia.
•-Patients who are pregnant or breast-feeding
•-Patients not competent to understand what the procedures involved
•-Patients with a personal history of melanoma or non-melanoma skin cancer
•-Patients with a first degree relative with melanoma skin cancer
•-Patients with atypical nevi.

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