NCT06709144进行中（未招募）3 期
Borderline of CME/D3 Dissection for Local Advanced Right-sided Colon Cancer(BLARCC): a Prospective, Multicenter Randomized Control Clinical Trial
Haixing Ju, MD1 个研究点 分布在 1 个国家目标入组 896 人开始时间: 2024年7月1日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 896
- 试验地点
- 1
- 主要终点
- 3 year DFS
研究概览
简要总结
The study was conducted on patients with advanced right-sided colon cancer, and the clinical pathological and prognostic data of the patients were compared between the two groups of patients who were randomly divided into those undergoing SMV and SMA left resection, with the aim of resolving the controversy over the left resection boundary of CME/D3 lymph node dissection through this study, and to clarify whether SMA left resection is superior to SMV left resection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 78 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •right side colon cancer(The primary lesion is located in the ileocecal region, ascending colon, hepatic flexure of colon, or proximal transverse colon)
- •T3-4 and/or N1-2M0
- •Colonoscopy and pathological biopsy confirmed colon adenocarcinoma
排除标准
- •Cannot undergo curative resection
- •Simultaneous multiple primary colorectal cancer or other diseases requiring segmental resection
- •Distant metastasis
- •Tumor invades surrounding organs, requiring joint organ resection
- •Emergency surgery is required for complications such as intestinal obstruction, perforation, and bleeding
- •Patients who have received neoadjuvant therapy before surgery
- •Pregnant or lactating women
- •Patients who are not suitable or unable to tolerate surgery
结局指标
主要结局
3 year DFS
时间窗: 3 years
3 year disease free survival
次要结局
- 5 year OS(5 years)
研究者
Haixing Ju, MD
Director
Zhejiang Cancer Hospital
研究点 (1)
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