Efficacy of Therapy With the Spironolactone Pills Compared to Minoxidil Lotion in Female Pattern Hair Loss

Phase 2

Completed

• Conditions: Female Pattern Hair Loss

• Registration Number: NCT00175617
• Lead Sponsor: University of British Columbia

Brief Summary

This study evaluates the efficacy of therapy with the anti-androgen spironolactone compared to topical minoxidil in female pattern hair loss.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09
• Study First Submitted: 2005-09-13
• Study First Submitted QC: 2005-09-13
• Study First Posted: 2005-09-15
• Primary Completion: 2009-03-09
• Study Completion: 2009-03-09
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-01
• Last Update Posted: 2017-03-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

• Subjects must be premenopausal women older than 18 with female pattern hair loss.

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Exclusion Criteria

• Androgen excess
• Other scalp or hair disorders
• Contraindications to spironolactone treatment, especially pregnancy, electrolyte imbalances, history of breast cancer, or intake of interfering drugs
• Contraindications to minoxidil treatment, especially patients who are allergic to this treatment or have a history of low blood pressure or irregular heart beats

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
hair density	after 3, 6 and 9 months

Secondary Outcome Measures

Name	Time	Method
percentage of subjects who experience side effects
subject assessment of treatment effect

Trial Locations

Locations (1)

UBC Division of Dermatology, Hair Research and Treatment Centre; 🇨🇦 Vancouver, British Columbia, Canada