Skip to main content
Clinical Trials/NCT06177795
NCT06177795
Completed
N/A

I-SCREEN: Increasing Screening for Cancer Using a Randomized Evaluation of EHR-based Nudges

Abramson Cancer Center at Penn Medicine2 sites in 1 country21,120 target enrollmentDecember 18, 2023
ConditionsBreast Cancer

Overview

Phase
N/A
Intervention
Not specified
Conditions
Breast Cancer
Sponsor
Abramson Cancer Center at Penn Medicine
Enrollment
21120
Locations
2
Primary Endpoint
Proportion of patients who complete a screening mammogram within 3 months after the visit
Status
Completed
Last Updated
9 months ago

Overview

Brief Summary

In this study, personalized nudges to clinicians and patients will be evaluated to help increase breast cancer screening rates in accordance with USPSTF guidelines among women with a primary care visit, with a particular emphasis on those at high risk for non-completion of cancer screening. In partnership with Penn Medicine (Penn) and Case Western Reserve University-University Hospitals (UH), two complementary, concurrent, 6-month, cluster-randomized, pragmatic trials will be conducted. Those assigned to the intervention arm will receive the following clinician and patient level nudge interventions: clinicians will receive a default pended order for a mammogram in the visit encounter in the EHR (Penn and UH), and patients will receive post-visit text message reminders to encourage them to schedule their mammogram (Penn). Patients identified as high risk for noncompletion will be individually randomized to receive an additional bidirectional text message nudge or the standard text messaging (Penn).

Detailed Description

Cancer is a leading cause of mortality in the United States. While strong USPSTF guideline recommendations support appropriate screening for early detection and to avoid preventable deaths, breast cancer screening is often underutilized. Increasing breast cancer screening rates is challenging, in part, because it requires complementary decisions from clinicians (e.g., recommend and counsel patients about screening) and patients (e.g., to internalize risks and choose to complete screening). Presently, the lack of interventions directly targeting both clinicians' and patients' decision-making may underscore the relatively stagnant screening rates in the United States. There is a significant need to develop and scale low-cost interventions that increase breast cancer screening while simultaneously addressing the needs of high-risk patients and reducing disparities. Building upon prior work, the investigators propose to develop and test EHR-based clinician and patient nudges, with an additional intensified nudge to high-risk patients, to help increase screening mammography rates. This study consists of two complementary and concurrent, cluster-randomized, pragmatic trials to be conducted at Penn and UH.

Registry
clinicaltrials.gov
Start Date
December 18, 2023
End Date
April 7, 2025
Last Updated
9 months ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Amol Navathe

Professor of Health Policy and Medicine

Abramson Cancer Center at Penn Medicine

Eligibility Criteria

Inclusion Criteria

  • All patients must meet the following criteria to be eligible:
  • Women between 40 and 74 years of age
  • A scheduled new or return (non-urgent/sick) primary care visit at one of the study practices (Penn Trial) or with one of the study primary care providers (UH Trial)
  • Are overdue and eligible for a mammogram per Health Maintenance
  • Does not have a future scheduled mammogram appointment
  • For the Penn Trial patient intensification nudge, at least one of the following criteria must be met to be considered high risk and randomized to receive the intensification nudge:
  • Medicare Insurance
  • Medicaid Insurance
  • No EHR patient portal account
  • Zero log-ins to EHR patient portal in the previous year

Exclusion Criteria

  • Patients will be excluded from the study if:
  • History of bilateral mastectomy
  • Have a mammogram exclusion modifier in Health Maintenance
  • Have no phone number (home or mobile) listed in their chart (Penn Trial only)

Outcomes

Primary Outcomes

Proportion of patients who complete a screening mammogram within 3 months after the visit

Time Frame: 3 months

The primary outcome is screening mammogram completion within 3 months after the first eligible primary care visit.

Secondary Outcomes

  • Proportion of patients who complete a screening mammogram within 6 months after the visit(6 months)

Study Sites (2)

Loading locations...

Similar Trials