The Montreal Cognitive Assessment as a Screening Tool for Preoperative Mild Cognitive Impairment in Geriatric Patients

• Conditions: Mild Cognitive Impairment

• Registration Number: NCT01496222
• Lead Sponsor: Mahidol University

Brief Summary

This is a prospective, double-blinded, control trial. The Montreal Cognitive Assessment is used to screen preoperative mild cognitive impairment in 582 consecutive geriatric patients, scheduled for general, vascular or urological surgery under general and/or regional anesthesia.

Detailed Description

At the preoperative visit, the co-researcher invites 322 general and vascular patients (male 190, female 132) and 260 urological patients (male 220, female 40) who meet the inclusion criteria to join the study. The process of the project is explained to the interested patients in details before an informed consent is obtained.

All participants are interviewed by using the Montreal Cognitive Assessment test. The history of drug used preoperatively (medication reconciliation) has also been recorded.

Study Timeline

• Study First Submitted: 2011-12-15
• Study First Submitted QC: 2011-12-18
• Study First Posted: 2011-12-21
• Study Start: 2012-01
• Primary Completion: 2015-10
• Status Verified: 2016-03
• Last Update Submitted: 2016-03-14
• Last Update Posted: 2016-03-16
• Study Completion: 2016-04

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 582

Inclusion Criteria

• male or female aged 65 yr, ASA I-III scheduled for elective general, vascular or urological surgery under general and/or regional anesthesia.

Exclusion Criteria

• unable to communicate in reading and writing
• psychosomatic patients
• insulin-dependant diabetes
• renal insufficiency (creatinine >1.5 mg/dL), renal dialysis
• uncontrolled congestive heart failure (American Heart Association Classification III or IV congestive heart failure), unstable angina, untreated cardiac arrhythmia
• active gastrointestinal bleeding.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of mild cognitive impairment in preoperative geriatric patients	1 Year

Secondary Outcome Measures

Name	Time	Method
Relationship between mild cognitive impairment and drug used preoperatively in geriatric patients	1 year	Pearson correlation coefficient will be used to evaluate the relationship between mild cognitive impairment and drug used preoperatively in geriatric patients.

Trial Locations

Locations (1)

Faculty of Medicine Siriraj Hospital; 🇹🇭 Bangkoknoi, Bangkok, Thailand