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Fabrication of novel polymer-ceramic bone substitute scaffolds using three-dimensional printing for alveolar ridge preservation : A preliminary clinical study

Phase 1
Recruiting
Conditions
Alveolar ridge deficiency Dimensional changes following an extraction
Scaffold, Polymer, Ceramic, Polycaprolactone, Biphasic calcium phosphate, Alveolar ridge preservation
Registration Number
TCTR20231107005
Lead Sponsor
Faculty of Dentistry Prince of Songkla University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
15
Inclusion Criteria

1. Healthy adult patients at least 20 years old (but no more than 65 years old), American Society of Anesthesiology (ASA) classification I-II.
2. The patients who planned for extracting un-restorable premolar or molar teeth followed with implant placement. Socket defect type in Elian classification I, IIa and IIb.
3. No severe periapical infection of extraction sites.
4. Patients are willing to participate and follow the study protocol.

Exclusion Criteria

1. The patient who has a severe periapical infection at extraction sites.
2. The patient with systemic diseases consists of uncontrolled DM, bleeding disorder, immunodeficiency, smoking habit, previous radiotherapy, or chemotherapy, and long-term taking bisphosphonate or steroid.
3. The patient is unable to follow the study protocol.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The dimensional changes of the alveolar ridge 5 Months Radiographic evaluation (CBCT images)
Secondary Outcome Measures
NameTimeMethod
Alveolar ridge volume changes 5 Months Volumetric analysis tool,The new bone formation 5 Months Histological analysis,Stability of dental implant 3 Months Implant Stability Quotient; ISQ
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