Vitamin D in Childhood Asthma
Not Applicable
- Conditions
- Health Condition 1: null- asthmatic children
- Registration Number
- CTRI/2015/06/005844
- Lead Sponsor
- Council of scientific Industrial Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 34
Inclusion Criteria
Age- Criteria: 5-16yrs
Intermittent Cough
Breathlessness
Recurrent Wheezing present
Response to bronchodilator present
Exclusion Criteria
1.interstitial lung disease
2.congenital heart disease
3. tuberculosis / Cystic fibrosis / HIV infection
4.Bronchomalacia / Laryngomalacia
6.Tracheo-esophageal fistula
7.Medications inducing chronic cough (ACEI)
8.Chronic liver / renal disease
9.Residing outside Delhi or unlikely to come for follow up
10.Frank vitamin D deficiency viz.Harrisonâ??s sulcus?
11.Patient have any chest wall deformity
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate the effect of vitamin D supplementation, on FEV1 in asthmatic children with vitamin D deficiency.Timepoint: To evaluate the effect of vitamin D supplementation, on FEV1 in asthmatic children with vitamin D deficiency. <br/ ><br>FEV1 will be monitored at 3months & 6months follow up period.
- Secondary Outcome Measures
Name Time Method i)To compare the following parameters (pre and post intervention ) asthmatic children with vitamin D deficiency on : <br/ ><br>1.Change in quality of life after vitamin D supplementation. <br/ ><br>2. Number of acute exacerbations <br/ ><br>3. Hospital emergency visits <br/ ><br>4. Number of hospitalisation <br/ ><br>ii)To study the trend of FEV1 in children without vitamin d deficiency. <br/ ><br>Timepoint: 3 & 6 months post intervention