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临床试验/NCT05311878
NCT05311878已完成不适用

Non-invasive Brain Computer Interface for Cognitive Enhancement

University of Texas at Austin1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2021年1月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
32
试验地点
1
主要终点
Change in correct answer rate of different rotation magnitudes across 5 intervention sessions

研究概览

简要总结

People's perceptual skills can significantly affect their abilities to make optimal decisions, judgments, and actions in real-world dynamic environments. Perceptual learning refers to training and experiences to induce improvements in the ability to make sense of what people see, hear, feel, taste or smell based on ambiguous sensory information. In this study, investigators hypothesise that there exist neural signatures that robustly encode the conscious visual perception of rotations of a cursor and the magnitudes of these rotations in a novel, rotation-based perceptual learning task. Investigators also hypothesise that online, instantaneous EEG-based feedback on subjects' visual perceptions of rotations with an EEG-based Brain Computer Interface (BCI) can foster perceptual learning much more effectively than behaviour perceptual training, especially in very small rotation magnitudes that represent extremely difficult perceptual tasks.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者
是

入选标准

  • •Able-bodied volunteers:
  • •good general health
  • •normal or corrected vision
  • •no history of neurological/psychiatric disease
  • •ability to read and understand English
  • •ability to understand information and ability to give a free and informed consent
  • •Subjects with neuropsychiatric diseases
  • •Subjects with neuropsychiatric diseases such as bipolar disorder and schizophrenia.
  • •normal or corrected vision
  • •ability to read and understand English
  • •ability to understand information and ability to give a free and informed consent

排除标准

  • •short attentional spans or cognitive deficits that prevent to remain concentrated during the experimental sessions
  • •concomitant serious illnesses (e.g., metabolic disorders, cardiac arrest)
  • •factors hindering proper EEG acquisition (e.g., scalp wound, uncontrolled muscle activity)

研究组 & 干预措施

EEG based perceptual training

Experimental

Subjects complete a perceptual learning task in which EEG-based visual feedback is provided

干预措施: EEG-based perceptual training (Device)

Behavior based perceptual training

Active Comparator

Subjects complete a perceptual learning task in which ground truth visual feedback is provided

干预措施: Behavior based perceptual training (Device)

结局指标

主要结局

Change in correct answer rate of different rotation magnitudes across 5 intervention sessions

时间窗: Difference is measured every 24 hours, before versus after each intervention session

The correct answer rate per rotation magnitude reflects the improvements in perceptual skills across the two conditions. It measures the percentage of each rotation magnitude spotted correctly. The score is 0-100, and the higher the value, the better the outcome.

次要结局

  • Change in neural correlates of conscious perception across 5 intervention sessions(Difference is measured every 24 hours, before versus after each intervention session)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jose del R. Millan

Professor

University of Texas at Austin

研究点 (1)

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