The Influences of Dry Eye Disease on Optical Quality

Completed

• Conditions: Dry Eye; Vision; Disturbance, Hysterical

• Registration Number: NCT04043949
• Lead Sponsor: Peking University Third Hospital

Brief Summary

DED could result in visual disturbance and damage optical quality. We aimed to evaluate the influences of dry eye disease (DED) on optical quality and their correlations.

Detailed Description

This study is aimed at evaluating changes of optical quality in dry eye patients with superficial punctate keratopathy after being treated by artificial lubricant and anti-inflammatory eye drops.

Study Timeline

• Study Start: 2017-07-01
• Status Verified: 2017-12
• Primary Completion: 2018-07-01
• Study Completion: 2018-07-01
• Study First Submitted: 2018-12-05
• Study First Submitted QC: 2019-07-31
• Last Update Submitted: 2019-07-31
• Study First Posted: 2019-08-02
• Last Update Posted: 2019-08-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 90

Inclusion Criteria

1. patients were diagnosed as dry eye according to the criteria provided by the Dry Eye Workshop (DEWS)
2. positive corneal fluorescein staining (CFS)
3. best-corrected distance visual acuity better than 20/20.

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Exclusion Criteria

History of ocular surgeries, contact lens wear, meibomian gland dysfunction, and any type of corneal scarring such as dystrophies or infections.

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Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
High order abberations	2017.7-2019.7	cornela high order abberations of patients
The severity of DED influenced the optical quality of dry eye patients	2017.7-2019.7	The optical quality of dry eye patients

Trial Locations

Locations (1)

Peking University Third Hospital; 🇨🇳 Beijing, Beijing, China