跳至主要内容
临床试验/CTRI/2025/07/090584
CTRI/2025/07/090584尚未招募2 期

A Clinical Study to Evaluate the Efficacy of Madhuka Ghrita Lepana in Nipple Crack in Lactatig women

Rajarajeshwari Ayurvedic Medical College Hospital and PG Center1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年7月28日最近更新:

试验速览

阶段
2 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
To know the Efficacy of Madhuka ghrita lepana in Nipple crack in Lactating women

研究概览

简要总结

NEED FOR THE STUDY:

 Nipple areolar complex appears painful due to loss of surface epithelium with formation of raw area or due to

a fissure at tip or base of nipple.These two conditions frequently co-exist and is termed as cracked nipple.1In ayurveda nipple crack can be correlated with ‘Ghrista sadyovrana as it is characterized by vigatatwak

occurring due to gharshana or abhighata.

 Acharya charaka  mentioned about stana sampat laxanas  in shareera sthana 8th chapter 53 sloka as stana

should not be situated at very high level,they should  not  hang very loose,they should neither be very lean

nor very plump.  They should have nipples of proportionate size. The child should find it easy to suckle them.3

 Cracked nipple is extremely painful when infants sucks,that interferes breast feeding and cause premature weaning.when infected,it may spread to deeper tissue producing mastitis.4 In Astanga Hrudaya utharsthanamsadhyovrana pratishedhan adhyayam a reference about madhukaghrita is explained.5

 The study drug madhuka (Glycyrrhiza glabra) is vrana Shodhana ropanaand varnakrit.6 It possess anti-inflammatory ,and antioxidant properties,itcontains glycyrrheinitic acid which promote the migration of

dermal fibroblast and promotes wound healing.7 Cracked nipple means any type of damage to nipple or

around areolar region associated with or without pain.It appears as cracks/ small lacerations or breaks on

skin of nipple.8

 Contemporary treatments includes usage of glycerine nipple pads, nipple shields,creams,lotions,ointments

( eg Lanolin ).The incidence of nipple crack is higher with in first 30days of postpartum period.

Prevalence rate of nipple crack shows that 32% mothers is having cracked nipple with in first month of postpartum period.9Among them 80-90% experience nipple pain that can results in early weaning. Ongoing research works in the field of nipple crack still prove that herbal preparations with peppermint,pisticiaatlantica showed better result than lanolin.Even though nipple crack is effectively managed in ayurveda ,systematic assessment and documentation has not been done.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
20.00 Year(s) 至 40.00 Year(s)(—)
性别
Female

入选标准

  • Lactating women 1.Who are between 20 to 40 years 2.Having nipple crack and pain 3.Irrespective of nature of Delivery 4.Nipple trauma score-3.

排除标准

  • Lactating women with symptoms of 1.Mastitis 2 Histroy of Breast abscess 3.Known case of Dermatological disorders 4.Known case of Nipple abnormalites.

结局指标

主要结局

To know the Efficacy of Madhuka ghrita lepana in Nipple crack in Lactating women

时间窗: 7 days

次要结局

  • To evaluate the Efficacy of Madhuka ghrita lepana in Nipple crack in Lactating women(7days)

研究者

发起方
Rajarajeshwari Ayurvedic Medical College Hospital and PG Center
申办方类型
Private medical college
责任方
Principal Investigator
主要研究者

DR Veena G Kadeli

Rajarajeshwari Ayurvedic Medical College Hospital and PG Center Humnabad Bidar

研究点 (1)

Loading locations...

相似试验