Improving knee joint stability in osteoarthritis with exercise therapy: does it work?
- Conditions
- osteoarthitis, knee, joint instability, elderly, physical functioning, pain, laxity, proprioception, muscle strength, walking.artrose, knie, gewrichtsinstabiliteit, ouderen, fysiek functioneren, pijn, laxiteit, propriocepsis, spierkracht, lopen.
- Registration Number
- NL-OMON28274
- Lead Sponsor
- This study will be carried out by the VU University Medical Centre (VUmc) and Jan van Breemen Institute in Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
21-12-2011 Changes:
1. Diagnosis of knee OA according to the clinical ACR criteria, i.e.: knee pain and at least three of the following six: age > 50 years, morning stiffness <30 minutes, crepitus, bony tenderness, bony enlargement and no palpable warmth.
Exclusion Criteria
1. Co-morbidity which clearly affects functional ability.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 21-12-2011 Changes:<br>The primary outcome measure in this RCT is self-reported physical functioning as assessed with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC).
- Secondary Outcome Measures
Name Time Method 21-12-2011 Changes:<br>A number of secondary outcome measures are included in the study, reflecting both the assessment of disabilities in specific daily activities, the patient perspective, and relevant biomechanical factors.<br /> These measures are:<br /><br>- perceived global effect (7-point Likert scale)<br /><br>- pain intensity (0-10 NRS)<br /><br>- stiffness (WOMAC)<br /><br>- fatigue (0-10 NRS)<br /><br>- Fitzgerald’s self-reported knee joint instability scale<br /><br>- proprioception<br /><br>- laxity<br /><br>- isokinetic muscle strength of the upper leg (BioDex)<br /><br>- frontal plane alignment of the knee (goniometer)<br /><br>- observed walking and transfer ability as assessed with the Get Up and Go (GUG) test