Minimizing Ventricular Pacing
Not Applicable
- Conditions
- Sinus Node Disease.First Degree Atrioventricular Block.
- Interventions
- Device: Prolonging atrioventricular (AV) delay.Device: Standard atrioventricular (AV) delay.
- Registration Number
- NCT01611389
- Lead Sponsor
- Military Institute od Medicine National Research Institute
- Brief Summary
The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality of life and other heart failure measures.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- prolonged PQ interval > 200 ms,
- percentage of right ventricular pacing with standard AV delay > 90.
Exclusion Criteria
- second or third degree atrioventricular block,
- permanent atrial fibrillation.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description Long AV delay. Prolonging atrioventricular (AV) delay. - Short AV delay. Standard atrioventricular (AV) delay. -
- Primary Outcome Measures
Name Time Method Oxygen uptake (cardiopulmonary exercise testing). 3 months
- Secondary Outcome Measures
Name Time Method Left ventricular ejection fraction. 3 months Assessed in echocardiography.
Quality of life 3 months SF36 questionnaire.
Arrhythmia 3 months 24 hours Holter monitoring, pacemaker storage data.
Ventilatory anaerobic threshold (cardiopulmonary exercise testing) 3 months VE/VCO2 slope (cardiopulmonary exercise testing). 3 months
Trial Locations
- Locations (1)
Military Institute of Medicine
🇵🇱Warsaw, Poland