NCT01611389UnknownNot Applicable
Minimizing Right Ventricular Pacing in Dual-chamber Pacemaker Patients With Sinus Node Disease and First Degree Atrioventricular Block.
Military Institute od Medicine National Research Institute2 sites in 1 country60 target enrollmentStarted: September 1, 2010Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 60
- Locations
- 2
- Primary Endpoint
- Oxygen uptake (cardiopulmonary exercise testing).
Study Overview
Brief Summary
The aim of this study is to evaluate the effect of minimizing right ventricular pacing in dual-chamber pacemaker patients with sinus node disease (SND) and first degree atrioventricular block (AVIB)on exercise capacity, quality of life and other heart failure measures.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 40 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •prolonged PQ interval > 200 ms,
- •percentage of right ventricular pacing with standard AV delay > 90.
Exclusion Criteria
- •second or third degree atrioventricular block,
- •permanent atrial fibrillation.
Outcomes
Primary Outcomes
Oxygen uptake (cardiopulmonary exercise testing).
Time Frame: 3 months
Secondary Outcomes
- Left ventricular ejection fraction.(3 months)
- Quality of life(3 months)
- Arrhythmia(3 months)
- Ventilatory anaerobic threshold (cardiopulmonary exercise testing)(3 months)
- VE/VCO2 slope (cardiopulmonary exercise testing).(3 months)
Investigators
Study Sites (2)
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