Effect of Topical Gabapentin in Itching

Not Applicable

Recruiting

• Conditions: macular amyloidosis.; Other amyloidosis; E85.8

• Registration Number: IRCT20131119015455N4
• Lead Sponsor: Esfahan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: Female
• Target Recruitment: 40

Inclusion Criteria

Clinical diagnosis of macular amyloidosis
Age range from 18 to 50 years
Corneal skin lesion in the back
No history of treatment in the past 6 months
Consent to attend to this study
No history of gabapentin allergy
No interference with other patient medications

Exclusion Criteria

Pregnancy
Breastfeeding
Inability to take medication
Renal failure
Depression
Neurological diseases

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Itching severity. Timepoint: Before intervention and 2, 4 , 6 weeks after intervention with topical Gabapentin. Method of measurement: 12- item severity pruritus scale and 4- item itching questioner.;Pigmentation rate. Timepoint: Before intervention and 2, 4 , 6 weeks after intervention with Gabapentin. Method of measurement: Photo finder system.

Secondary Outcome Measures

Name	Time	Method
Patient satisfaction. Timepoint: Six month after treatment. Method of measurement: patient satisfaction Visual Analogue Scale score.;Topical side effects of drug use. Timepoint: Four, 8, 12 weeks and 6 months after intervention. Method of measurement: Clinical evaluation.