Effect of a Combined Use of Mosquito Repellent and Insecticide Treated Net on Malaria in Ethiopia

Phase 4

Completed

• Conditions: Malaria; Mosquito Repellent; Long Lasting Insecticidal Nets
• Interventions: Other: Mosquito repellent

• Registration Number: NCT01160809
• Lead Sponsor: Malaria Consortium, Ethiopia

Brief Summary

The combined use of a mosquito repellent and long lasting insecticidal nets (LLINs) by household members would result in a 40% reduction in malaria prevalence compared with households that only use LLINs.

Detailed Description

It has been recognized that the use of malaria preventive measures in combination with LLINs could improve the effectiveness of nets in preventing the disease. This study examined the effect of a combined use of mosquito repellent (i.e., Buzz Off) and LLINs on malaria prevalence in an area of unstable and seasonal malaria transmission.

Study Timeline

• Study Start: 2008-09
• Primary Completion: 2008-12
• Study Completion: 2009-01
• Status Verified: 2010-07
• Study First Submitted: 2010-07-08
• Study First Submitted QC: 2010-07-09
• Last Update Submitted: 2010-07-09
• Study First Posted: 2010-07-12
• Last Update Posted: 2010-07-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 6082

Inclusion Criteria

• All volunteer household members

Exclusion Criteria

• Infants less than two months
• Not in the study area

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Mosquito repellent and LLINs group vs. LLINs group only	Mosquito repellent	This study is based on two population groups: 1) a group of households that use LLINs alone (control) and 2) a group of households that use both mosquito repellent and LLINs (repellent group).

Primary Outcome Measures

Name	Time	Method
Malaria parasite (P. falciparum and/or P. vivax)through microscopic detection		The objective of the study is to investigate the impact of a combined use of mosquito repellent and LLINs in reducing malaria. The primary outcome of the study is detection of malaria parasites (P. falciparum and/or P. vivax) through examination of microscopic blood slides collected from finger-pricks.

Secondary Outcome Measures

Name	Time	Method
Household ownership and utilization of LLINs		Owneship and utilization of LLINs by household members during the night before the baseline survey

Trial Locations

Locations (1)

SNNPR, Ethiopia; 🇪🇹 Awassa, Snnpr, Ethiopia