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Clinical Trials/NCT03469778
NCT03469778
Unknown
Not Applicable

Assessment of a Upper Limb Robotic Device in Stroke Patients

University of Sao Paulo General Hospital1 site in 1 country10 target enrollmentMay 2, 2018
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
University of Sao Paulo General Hospital
Enrollment
10
Locations
1
Primary Endpoint
Fugl Meyer Assessment Upper Limb (FMA-UL)
Last Updated
8 years ago

Overview

Brief Summary

The objectives of this phase II clinical study are: evaluate the efficacy, safety, patient adeherence and clinical applicability of a new robotic device for patients with stroke at a physical rehabilitation institution (Instituto de Medicina Física e Reabilitação do Hospital das Clínicas da Universidade de São Paulo - IMREA HCFMUSP - Rede de Reabilitação Lucy Montoro, unidade Vila Mariana). Methods: 10 patients with stroke diagnosis and Fugl-Meyer score ranging from 34 to 55 will be selected to be included in the study. After signing the informed consent form and being assessed by the baseline evaluations, they will undertake 18 sessions of robotic therapy, which in its turn will be prescribed three times a week. After this period, the patients will be evaluated for future comparison of both the pre-treatment and final assessments.

Registry
clinicaltrials.gov
Start Date
May 2, 2018
End Date
September 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Joint, muscle or tendinous lesions and/or pain that can occur during the intervention and make it difficult or impossible to perform robotic tasks.
  • Progressive worsening of spasticity.
  • Withdrawal of the informed consent form.
  • New episode of stroke.
  • Comorbidities that may occur during interventions such as hypertension, seizures, diabetes, among other uncontrolled clinical issues.

Outcomes

Primary Outcomes

Fugl Meyer Assessment Upper Limb (FMA-UL)

Time Frame: Mean change from baseline at six weeks (19 sessions of robotic therapy).

FMA-UL evaluates the recovery of the hemiplegic patient after stroke. It includes the measurement of reflex activity, movement with and without synergy, voluntary movements and coordination of shoulder, elbow, wrist, hand.

Secondary Outcomes

  • Wolf Motor Function Test (WMFT)(Mean change from baseline at six weeks (19 sessions of robotic therapy).)
  • Dynamometry - Grasp and Pinch(Mean change from baseline at six weeks (19 sessions of robotic therapy).)
  • Patients safety(Adverse effects reported during 6 weeks treatment.)
  • Treatment adherence(Drop outs reported during 6 weeks treatment.)

Study Sites (1)

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