Predicting success of nasal high flow therapy in emergency patients with acute hypoxemic respiratory failure by ROX index

Phase 3

Active, not recruiting

• Conditions: acute hypoxemic respiratory failure in emergency patients; acute hypoxemic respiratory failure; nasal high flow therapy; high flow nasal cannula; emergency patients

• Registration Number: TCTR20180829006
• Lead Sponsor: Siriraj Research Fund, Faculty of medicine, Siriraj Hospital, Mahidol University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-08-29
• Study Completion: 2019-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

respiratory rate more than 24 breaths/min
use of accessory muscle use or abdominal paradox
room air SpO2 equal or less than 90% and need of oxygen supplement via face mask more than 9L/min to maintain SpO2 above 92%

Exclusion Criteria

cardiac arrest, arrhythmia, ST-elevation myocardial infarction, respiratory arrest, need for immediate intubation, Glasglow Coma Scale (GCS) <12, hemodynamic instability (systolic blood pressure <90 mmHg or mean arterial pressure < 65 mmHg, respiratory acidosis (pH <7.3 and PaCO2 >50 mmHg), suspected hypercapnic respiratory failure (chronic obstructive pulmonary disease, obstructive sleep apnea), RR >35 breaths/min or SpO2 <90% despite oxygen supplement via facemask >9 L/min, pneumothorax and palliative patients

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
accuracy of ROX index 48 hours after treatment area under the curve

Secondary Outcome Measures

Name	Time	Method
factor influence success rate of nasal high flow therapy no factors,emergency length of stay no hours,hospital length of stay no hours,mortality rate no percentage