Study comparing two methods of abortion in second trimester using misoprostol or ethacridine lactate after priming with mifepristone
Not Applicable
Completed
- Conditions
- Health Condition 1: null- SECOND TRIMESTER ABORTIONS
- Registration Number
- CTRI/2018/01/011157
- Lead Sponsor
- Project in the Department of Obstetrics and Gynecology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
1.Second trimester abortions for medical, social, eugenic reasons
2.Intrauterine pregnancy
3.18-40 years
4.Consent to participate in the study
Exclusion Criteria
1.Less than 13 weeks and more than 20 weeks pregnancy terminations
2.Patients with history of renal disease or hepatic disease or bronchial asthma or hematological disease or glaucoma or heart disease etc
3.Hemoglobin less than 10 gm/dl
4.Patients with previous caesarean section and other uterine scars
5.Symptomatic reproductive tract infections
6.Hypersensitivity to mifepristone or misoprostol or ethacridine lactate or oxytocin
7.Rupture of membranes
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Success rate ( percentage of complete abortions within 24 hours of using the drug ). <br/ ><br>2. Induction abortion interval (the time from usage of misoprostol/ethacridine to expulsion of fetus and placenta) <br/ ><br>Timepoint: 11. Success rate ( percentage of complete abortions within 24 hours of using the drug ). <br/ ><br>2. Induction abortion interval (the time from usage of misoprostol/ethacridine to expulsion of fetus and placenta) <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. Side effects ( nausea, vomitting, flatulence, dyspepsia, diarrhea, constipation, headache, heavy menstrual bleeding, hypersensitivity, pyrexia, etc.) <br/ ><br>2. Patients satisfaction and pain ( numerical scale) <br/ ><br>3. Requirement of check curettage <br/ ><br>4. Difference of pre procedure and post procedure hematocrit <br/ ><br>5. Blood loss and requirement of transfusion.Timepoint: NONE