Effect of tomato supplementation on oxidative stress and cardiac function in hemodialysis patients
Not Applicable
- Conditions
- Chronic kidney failure unspecified
- Registration Number
- RBR-9x5whvf
- Lead Sponsor
- Faculdade de Medicina de Botucatu UNESP
- Brief Summary
In this study, it was possible to observe that lycopene supplementation with cooked tomatoes for 12 weeks was able to reduce the concentration of carbonyl protein, an important marker of oxidative damage.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Data analysis completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Patients older than 18 years old and prevalent in chronic HD for at least three months were included;
Exclusion Criteria
Patients with cancer, HIV-positive undergoing antiretroviral therapy, end-stage liver disease, heart failure disease with ejection fraction less than 30%, clinical diagnosis of acute infection, (or using antibiotics), chronic inflammatory diseases, such as systemic lupus erythematosus and chronic obstructive pulmonary disease.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in the serum concentration of MDA ;Reduction in the serum concentration of carbonylated protein
- Secondary Outcome Measures
Name Time Method Change in posterior wall thickness (hypertrophy);Change in the frequency of presence of atheromatous plaque