Multimodal Pulmonary Rehabilitation in Radiographic Axial Spondyloarthritis: A Prospective Pilot Study Addressing Mechanical Restriction and Functional Capacity
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Change in 6-Minute Walk Distance (6MWD)
研究概览
简要总结
This prospective pilot study aims to evaluate the efficacy of a structured 8-week multimodal pulmonary rehabilitation (PR) program specifically designed for patients with radiographic axial spondyloarthritis (r-axSpA). The study assesses the impact of a composite intervention incorporating aerobic conditioning, resistance training, flexibility protocols, and targeted diaphragmatic breathing on functional exercise capacity, dyspnea severity, and pulmonary function.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age between 18 and 75 years.
- •Diagnosis of radiographic axial spondyloarthritis (r-axSpA) confirmed according to the Modified New York Criteria.
- •Clinical stability without acute flares or escalation of systemic therapy in the preceding 3 months.
- •Ability to perform spirometry and ambulate safely.
排除标准
- •Primary respiratory disorders (e.g., COPD and interstitial lung disease) acting as the primary cause of limitation.
- •Significant cardiovascular contraindications to exercise.
- •Pregnancy.
- •Participation in a structured rehabilitation program within the last 3 months.
研究组 & 干预措施
Multimodal Pulmonary Rehabilitation
Patients with radiographic axial spondyloarthritis (r-axSpA) receiving an 8-week structured multimodal pulmonary rehabilitation program.
干预措施: Multimodal Pulmonary Rehabilitation (Behavioral)
结局指标
主要结局
Change in 6-Minute Walk Distance (6MWD)
时间窗: Baseline and Week 8
Functional exercise capacity is measured by the total distance walked in 6 minutes, recorded in meters. Higher values indicate better functional exercise capacity (better outcome).
次要结局
- Change in Forced Vital Capacity (FVC)(Baseline and Week 8)
- Change in Borg Dyspnea Scale(Baseline and Week 8)
- Change in BASFI Score(Baseline and Week 8)
- Change in SF-36 Mental Health Score(Baseline and Week 8)
研究者
Ender Salbaş
Assistant Professor
Balikesir University