Impact of Vitamin D Level and Supplement on SLE Patients During COVID-19 Pandemic
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 38
- 试验地点
- 1
- 主要终点
- Level of serum vitamin D in SLE infected with COVID-19
研究概览
简要总结
Aim of the work Impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection, duration of COVID-19 disease course, fatigue development as a complication for both SLE and COVID-19 and assess impact of prior chloroquine on COVID-19 disease outcomes Patients and methods 38 SLE patients previously diagnosed and on different lines of lupus management. Participants were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Serum vit D was measured in serum by ELISA.
详细描述
Primary objective: assess the impact of serum vit D level in SLE patients with COVID-19 disease on severity of infection and pandemic treatment outcome.
Secondary objectives:
- Effect of serum vit D level in SLE patients on duration of COVID-19 disease course and fatigue development as a complication for both SLE and COVID-19
- Impact of prior chloroquine on COVID-19 disease outcomes
- Correlation of serum vit D level with different laboratory investigations at time of COVID-19 outbreak
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- SLE patients previously diagnosed
- •Patients are not suffering from malignancies.
- •Patients have no organ failure nor uncontrolled medical illness.
- •Recent COVID-19 infection
排除标准
- •- Pregnant, lactating females
- •Concurrent malignancies
- •Patients with other autoimmune disease
研究组 & 干预措施
SLE patients
SLE patients were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Vit D was measured in serum by ELISA. Vit D was added to anti COVID-19.
干预措施: Vitamin D (Drug)
SLE patients
SLE patients were presented to chest outpatient clinic and emergency hospital, Mansoura University with manifestation suggesting COVID-19 infection. Vit D was measured in serum by ELISA. Vit D was added to anti COVID-19.
干预措施: ELISA (Diagnostic Test)
结局指标
主要结局
Level of serum vitamin D in SLE infected with COVID-19
时间窗: 6 months
Measurement of serum vit D level (ng/ml)
次要结局
- Vitamin D level with COVID-19 severity(6 months)
研究者
Yasmin Adel Abdelsalam Hussein
Lecturer of Rheumatology and Rehabilitation
Mansoura University