A study to reveal the actual clinical features of chronic constipation and to evaluate the efficacy of therapeutic drugs on chronic constipatio
Not Applicable
- Conditions
- Chronic constipation
- Registration Number
- JPRN-UMIN000035794
- Lead Sponsor
- Others Department of Laboratory Medicine, The Jikei University Daisan Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 800
Inclusion Criteria
Not provided
Exclusion Criteria
(1) Alarm feature such as vomiting, gastrointestinal tract bleeding, (includes hematemesis, bloody stool, anemia, etc.) or rapid weight loss (2) History of gastrointestinal tract resection or vagotomy (3) Any other disease or previous surgery which may influence the results of questionnaire more than chronic constipation (4) Any organ failure or mental disease (5) Confirmed or suspected malignancy (6) Pregnancy, possible pregnancy, or breastfeeding (7) Judged as irrelevant by the responsible doctor of this study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The actual clinical features of chronic constipation explored by several questionnaires such as CC-TEST, Constipation Scoring System (CSS), Hospital Anxiety and Depression Scale (HADS), and Short Form-8 (SF-8). The efficacy of the therapeutic drugs on chronic constipation. The reliability and validity of the newly developed questionnaire for chronic constipation, CC-TEST. Outcome measures evaluation using questionnaires were performed at baseline, at 2 weeks and at 4 weeks after medication.
- Secondary Outcome Measures
Name Time Method The effect of each constipation symptoms on patients' dairy life. Comparison of the efficacy of therapeutic drugs on chronic constipation among the groups divided by their mechanism of action. The relationship between the patients' background factors and the clinical features of chronic constipation.